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PDE5 inhibitors as therapeutics for heart disease, diabetes and cancer

The phosphodiesterase 5 (PDE5) inhibitors, including sildenafil (Viagra™), vardenafil (Levitra™), and tadalafil (Cialis™) have been developed for treatment of erectile dysfunction. Moreover, sildenafil and tadalafil are used for the management of pulmonary arterial hypertension in patients. Since ou...

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Detalles Bibliográficos
Publicado en:Pharmacol Ther
Autores principales: Das, Anindita, Durrant, David, Salloum, Fadi N, Xi, Lei, Kukreja, Rakesh C
Formato: Artigo
Lenguaje:Inglês
Publicado: 2014
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4494657/
https://ncbi.nlm.nih.gov/pubmed/25444755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pharmthera.2014.10.003
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