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Metabolic regulator LKB1 plays a crucial role in Schwann cell-mediated axon maintenance
Schwann cells (SCs) promote axonal integrity independently of myelination by poorly understood mechanisms. Current models suggest that SC metabolism is critical for this support function and that SC metabolic deficits may lead to axonal demise. The LKB1-AMPK kinase pathway targets multiple downstrea...
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| Publicado no: | Nat Neurosci |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4494117/ https://ncbi.nlm.nih.gov/pubmed/25195104 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.3809 |
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