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mTORC1 promotes proliferation of immature Schwann cells and myelin growth of differentiated Schwann cells
The myelination of axons in peripheral nerves requires precisely coordinated proliferation and differentiation of Schwann cells (SCs). We found that the activity of the mechanistic target of rapamycin complex 1 (mTORC1), a key signaling hub for the regulation of cellular growth and proliferation, is...
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| Foilsithe in: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , |
| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
National Academy of Sciences
2017
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5448230/ https://ncbi.nlm.nih.gov/pubmed/28484008 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1620761114 |
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