Loading...

Potentiation of Growth Inhibitory Responses of the mTOR Inhibitor Everolimus by Dual mTORC1/2 Inhibitors in Cultured Breast Cancer Cell Lines

The mammalian target of rapamycin (mTOR), a vital component of signaling pathways involving PI3K/AKT, is an attractive therapeutic target in breast cancer. Everolimus, an allosteric mTOR inhibitor that inhibits the mTOR functional complex mTORC1, is approved for treatment of estrogen receptor positi...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Leung, Euphemia Y., Askarian-Amiri, Marjan, Finlay, Graeme J., Rewcastle, Gordon W., Baguley, Bruce C.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4492962/
https://ncbi.nlm.nih.gov/pubmed/26148118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0131400
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!