Afatinib efficacy against squamous cell carcinoma of the head and neck cell lines in vitro and in vivo

Epidermal growth factor receptor (EGFR) inhibitors have demonstrated efficacy in squamous cell carcinoma of the head and neck (SCCHN). In addition to EGFR, other ErbB family members are expressed and activated in SCCHN. Afatinib is an ErbB family blocker that has been approved for treating patients...

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Detalhes bibliográficos
Publicado no:Target Oncol
Main Authors: Young, Natalie R., Soneru, Christian, Liu, Jing, Grushko, Tatyana A., Hardeman, Ashley, Olopade, Olufunmilayo I., Baum, Anke, Solca, Flavio, Cohen, Ezra E. W.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2015
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4492891/
https://ncbi.nlm.nih.gov/pubmed/25559287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11523-014-0353-6
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