Afatinib efficacy against squamous cell carcinoma of the head and neck cell lines in vitro and in vivo

Epidermal growth factor receptor (EGFR) inhibitors have demonstrated efficacy in squamous cell carcinoma of the head and neck (SCCHN). In addition to EGFR, other ErbB family members are expressed and activated in SCCHN. Afatinib is an ErbB family blocker that has been approved for treating patients...

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Publicat a:Target Oncol
Autors principals: Young, Natalie R., Soneru, Christian, Liu, Jing, Grushko, Tatyana A., Hardeman, Ashley, Olopade, Olufunmilayo I., Baum, Anke, Solca, Flavio, Cohen, Ezra E. W.
Format: Artigo
Idioma:Inglês
Publicat: Springer International Publishing 2015
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4492891/
https://ncbi.nlm.nih.gov/pubmed/25559287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11523-014-0353-6
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