Afatinib efficacy against squamous cell carcinoma of the head and neck cell lines in vitro and in vivo

Epidermal growth factor receptor (EGFR) inhibitors have demonstrated efficacy in squamous cell carcinoma of the head and neck (SCCHN). In addition to EGFR, other ErbB family members are expressed and activated in SCCHN. Afatinib is an ErbB family blocker that has been approved for treating patients...

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Bibliografische gegevens
Gepubliceerd in:Target Oncol
Hoofdauteurs: Young, Natalie R., Soneru, Christian, Liu, Jing, Grushko, Tatyana A., Hardeman, Ashley, Olopade, Olufunmilayo I., Baum, Anke, Solca, Flavio, Cohen, Ezra E. W.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Springer International Publishing 2015
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Original Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4492891/
https://ncbi.nlm.nih.gov/pubmed/25559287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11523-014-0353-6
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