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Afatinib radiosensitizes head and neck squamous cell carcinoma cells by targeting cancer stem cells

The dismal prognosis of locally advanced and metastatic squamous cell carcinoma of the head and neck (HNSCC) is primarily due to the development of resistance to chemoradiation therapy (CRT). Deregulation of Epidermal Growth Factor Receptor (EGFR) signaling is involved in HNSCC pathogenesis by regul...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Macha, Muzafar A, Rachagani, Satyanarayana, Qazi, Asif Khurshid, Jahan, Rahat, Gupta, Suprit, Patel, Anery, Seshacharyulu, Parthasarathy, Lin, Chi, Li, Sicong, Wang, Shuo, Verma, Vivek, Kishida, Shosei, Kishida, Michiko, Nakamura, Norifumi, Kibe, Toshiro, Lydiatt, William M, Smith, Russell B, Ganti, Apar K, Jones, Dwight T, Batra, Surinder K, Jain, Maneesh
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5400558/
https://ncbi.nlm.nih.gov/pubmed/28423495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.15468
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