Afatinib radiosensitizes head and neck squamous cell carcinoma cells by targeting cancer stem cells

The dismal prognosis of locally advanced and metastatic squamous cell carcinoma of the head and neck (HNSCC) is primarily due to the development of resistance to chemoradiation therapy (CRT). Deregulation of Epidermal Growth Factor Receptor (EGFR) signaling is involved in HNSCC pathogenesis by regul...

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Bibliografische gegevens
Gepubliceerd in:Oncotarget
Hoofdauteurs: Macha, Muzafar A, Rachagani, Satyanarayana, Qazi, Asif Khurshid, Jahan, Rahat, Gupta, Suprit, Patel, Anery, Seshacharyulu, Parthasarathy, Lin, Chi, Li, Sicong, Wang, Shuo, Verma, Vivek, Kishida, Shosei, Kishida, Michiko, Nakamura, Norifumi, Kibe, Toshiro, Lydiatt, William M, Smith, Russell B, Ganti, Apar K, Jones, Dwight T, Batra, Surinder K, Jain, Maneesh
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Impact Journals LLC 2017
Onderwerpen:
Research Paper
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5400558/
https://ncbi.nlm.nih.gov/pubmed/28423495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.15468
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