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Guggulsterone decreases proliferation and metastatic behavior of pancreatic cancer cells by modulating JAK/STAT and Src/FAK signaling

Inadequate efficacy, high toxicity and drug resistance associated with existing chemotherapeutic agents mandate a need for novel therapeutic strategies for highly aggressive pancreatic cancer (PC). Guggulsterone (GS) exhibits potent anti-proliferative effects against various cancer cells and has eme...

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Bibliografische gegevens
Hoofdauteurs: Macha, Muzafar A., Rachagani, Satyanarayana, Gupta, Suprit, Pai, Priya, Ponnusamy, Moorthy P., Batra, Surinder K., Jain, Maneesh
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2013
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3825785/
https://ncbi.nlm.nih.gov/pubmed/23920124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2013.07.037
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