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Pathobiological Implications of Mucin Glycans in Cancer: Sweet Poison and Novel Targets

Mucins are large glycoproteins expressed on the epithelia that provide a protective barrier against harsh insults from toxins and pathogenic microbes. These glycoproteins are classified primarily as being secreted and membrane-bound; both forms are involved in pathophysiological functions including...

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Detalhes bibliográficos
Publicado no:Biochim Biophys Acta
Main Authors: Chugh, Seema, Gnanapragassam, Vinayaga S., Jain, Maneesh, Rachagani, Satyanarayana, Ponnusamy, Moorthy P., Batra, Surinder K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4663118/
https://ncbi.nlm.nih.gov/pubmed/26318196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbcan.2015.08.003
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