Afatinib efficacy against squamous cell carcinoma of the head and neck cell lines in vitro and in vivo

Epidermal growth factor receptor (EGFR) inhibitors have demonstrated efficacy in squamous cell carcinoma of the head and neck (SCCHN). In addition to EGFR, other ErbB family members are expressed and activated in SCCHN. Afatinib is an ErbB family blocker that has been approved for treating patients...

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Enregistré dans:
Détails bibliographiques
Publié dans:Target Oncol
Auteurs principaux: Young, Natalie R., Soneru, Christian, Liu, Jing, Grushko, Tatyana A., Hardeman, Ashley, Olopade, Olufunmilayo I., Baum, Anke, Solca, Flavio, Cohen, Ezra E. W.
Format: Artigo
Langue:Inglês
Publié: Springer International Publishing 2015
Sujets:
Original Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4492891/
https://ncbi.nlm.nih.gov/pubmed/25559287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11523-014-0353-6
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