Afatinib efficacy against squamous cell carcinoma of the head and neck cell lines in vitro and in vivo

Epidermal growth factor receptor (EGFR) inhibitors have demonstrated efficacy in squamous cell carcinoma of the head and neck (SCCHN). In addition to EGFR, other ErbB family members are expressed and activated in SCCHN. Afatinib is an ErbB family blocker that has been approved for treating patients...

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Publicado en:Target Oncol
Autores principales: Young, Natalie R., Soneru, Christian, Liu, Jing, Grushko, Tatyana A., Hardeman, Ashley, Olopade, Olufunmilayo I., Baum, Anke, Solca, Flavio, Cohen, Ezra E. W.
Formato: Artigo
Lenguaje:Inglês
Publicado: Springer International Publishing 2015
Materias:
Original Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4492891/
https://ncbi.nlm.nih.gov/pubmed/25559287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11523-014-0353-6
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