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Evidence that pregabalin reduces neuropathic pain by inhibiting the spinal release of glutamate

Pregabalin is an anticonvulsant that successfully treats many neuropathic pain syndromes, although the mechanism of its antihyperalgesic action remains elusive. This study aims to help delineate pregabalin’s antihyperalgesic mechanisms. We assessed the effectiveness of pregabalin at decreasing mecha...

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Detalles Bibliográficos
Publicado en:J Neurochem
Main Authors: Kumar, Naresh, Laferriere, Andre, Yu, Jonathan S.C., Leavitt, Amelia, Coderre, Terence J.
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4492734/
https://ncbi.nlm.nih.gov/pubmed/20132471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2010.06625.x
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