Evans Blue Reduces Neuropathic Pain Behavior by Inhibiting Spinal ATP Release

Upon peripheral nerve injury, vesicular ATP is released from damaged primary afferent neurons. This extracellular ATP subsequently activates purinergic receptors of the spinal cord, which play a critical role in neuropathic pain. As an inhibitor of the vesicular nucleotide transporter (VNUT), Evans...

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Detalhes bibliográficos
Main Authors: Yuhua Yin, Jinpyo Hong, Thuỳ Linh Phạm, Juhee Shin, Do Hyeong Gwon, Hyeok Hee Kwon, Nara Shin, Hyo Jung Shin, Sun Yeul Lee, Won-hyung Lee, Dong Woon Kim
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2019-09-01
Colecção:International Journal of Molecular Sciences
Assuntos:
Evans blue
neuropathic pain
spinal nerve ligation
vesicular nucleotide transporter
ATP
analgesic effect
Acesso em linha:https://www.mdpi.com/1422-0067/20/18/4443
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