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Metabotropic glutamate receptors (mGluRs) regulate noxious stimulus-induced glutamate release in spinal cord dorsal horn of rats with neuropathic and inflammatory pain

In rats with persistent pain, spinal group I metabotropic glutamate receptor (mGluR) activity has been shown to be pronociceptive, whereas spinal group II/III activity is antinociceptive. In brain, group I mGluR activity produces positive feedback effects on glutamate release, whereas group II/III a...

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Detalhes bibliográficos
Publicado no:J Neurochem
Main Authors: Kumar, Naresh, Laferriere, Andre, Yu, Jonathan S.C., Poon, Tanya, Coderre, Terence J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4486382/
https://ncbi.nlm.nih.gov/pubmed/20412385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2010.06761.x
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