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Pharmacodynamic assays to facilitate preclinical and clinical development of pre-mRNA splicing modulatory drug candidates
The spliceosome has recently emerged as a new target for cancer chemotherapy and novel antitumor spliceosome targeted agents are under development. Here, we describe two types of novel pharmacodynamic assays that facilitate drug discovery and development of this intriguing class of innovative therap...
Zapisane w:
| Wydane w: | Pharmacol Res Perspect |
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| Główni autorzy: | , , , , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
John Wiley & Sons, Ltd
2015
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4492733/ https://ncbi.nlm.nih.gov/pubmed/26171237 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prp2.158 |
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