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Epigenome-wide association study (EWAS) of BMI, BMI change and waist circumference in African American adults identifies multiple replicated loci

Obesity is an important component of the pathophysiology of chronic diseases. Identifying epigenetic modifications associated with elevated adiposity, including DNA methylation variation, may point to genomic pathways that are dysregulated in numerous conditions. The Illumina 450K Bead Chip array wa...

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Detalhes bibliográficos
Publicado no:Hum Mol Genet
Main Authors: Demerath, Ellen W., Guan, Weihua, Grove, Megan L., Aslibekyan, Stella, Mendelson, Michael, Zhou, Yi-Hui, Hedman, Åsa K., Sandling, Johanna K., Li, Li-An, Irvin, Marguerite R., Zhi, Degui, Deloukas, Panos, Liang, Liming, Liu, Chunyu, Bressler, Jan, Spector, Tim D., North, Kari, Li, Yun, Absher, Devin M., Levy, Daniel, Arnett, Donna K., Fornage, Myriam, Pankow, James S., Boerwinkle, Eric
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4492394/
https://ncbi.nlm.nih.gov/pubmed/25935004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddv161
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