Epigenome-wide study identifies novel methylation loci associated with body mass index and waist circumference

OBJECTIVE: To conduct an epigenome-wide analysis of DNA methylation and obesity traits. DESIGN AND METHODS: We quantified DNA methylation in CD4+ T-cells using the Illumina Infinium Human Methylation450 array in 991 participants of the Genetics of Lipid Lowering Drugs and Diet Network. We modeled me...

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Veröffentlicht in:Obesity (Silver Spring)
Hauptverfasser: Aslibekyan, Stella, Demerath, Ellen W., Mendelson, Michael, Zhi, Degui, Guan, Weihua, Liang, Liming, Sha, Jin, Pankow, James S., Liu, Chunyu, Irvin, Marguerite R., Fornage, Myriam, Hidalgo, Bertha, Lin, Li-An, Thibeault, Krista Stanton, Bressler, Jan, Tsai, Michael Y., Grove, Megan L., Hopkins, Paul N., Boerwinkle, Eric, Borecki, Ingrid B., Ordovas, Jose M., Levy, Daniel, Tiwari, Hemant K., Absher, Devin M., Arnett, Donna K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4482015/
https://ncbi.nlm.nih.gov/pubmed/26110892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/oby.21111
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