Epigenome-wide association study (EWAS) of BMI, BMI change and waist circumference in African American adults identifies multiple replicated loci

Obesity is an important component of the pathophysiology of chronic diseases. Identifying epigenetic modifications associated with elevated adiposity, including DNA methylation variation, may point to genomic pathways that are dysregulated in numerous conditions. The Illumina 450K Bead Chip array wa...

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Publicado en:Hum Mol Genet
Autores principales: Demerath, Ellen W., Guan, Weihua, Grove, Megan L., Aslibekyan, Stella, Mendelson, Michael, Zhou, Yi-Hui, Hedman, Åsa K., Sandling, Johanna K., Li, Li-An, Irvin, Marguerite R., Zhi, Degui, Deloukas, Panos, Liang, Liming, Liu, Chunyu, Bressler, Jan, Spector, Tim D., North, Kari, Li, Yun, Absher, Devin M., Levy, Daniel, Arnett, Donna K., Fornage, Myriam, Pankow, James S., Boerwinkle, Eric
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2015
Materias:
Association Studies Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4492394/
https://ncbi.nlm.nih.gov/pubmed/25935004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddv161
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