Epigenome-wide association study (EWAS) of BMI, BMI change and waist circumference in African American adults identifies multiple replicated loci

Obesity is an important component of the pathophysiology of chronic diseases. Identifying epigenetic modifications associated with elevated adiposity, including DNA methylation variation, may point to genomic pathways that are dysregulated in numerous conditions. The Illumina 450K Bead Chip array wa...

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Détails bibliographiques
Publié dans:Hum Mol Genet
Auteurs principaux: Demerath, Ellen W., Guan, Weihua, Grove, Megan L., Aslibekyan, Stella, Mendelson, Michael, Zhou, Yi-Hui, Hedman, Åsa K., Sandling, Johanna K., Li, Li-An, Irvin, Marguerite R., Zhi, Degui, Deloukas, Panos, Liang, Liming, Liu, Chunyu, Bressler, Jan, Spector, Tim D., North, Kari, Li, Yun, Absher, Devin M., Levy, Daniel, Arnett, Donna K., Fornage, Myriam, Pankow, James S., Boerwinkle, Eric
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2015
Sujets:
Association Studies Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4492394/
https://ncbi.nlm.nih.gov/pubmed/25935004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddv161
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