Efficient CRISPR/Cas9-Mediated Genome Editing in Mice by Zygote Electroporation of Nuclease

The clustered regularly interspaced short palindromic repeat (CRISPR)/CRISPR-associated protein (Cas) system is an adaptive immune system in bacteria and archaea that has recently been exploited for genome engineering. Mutant mice can be generated in one step through direct delivery of the CRISPR/Ca...

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發表在:Genetics
Main Authors: Qin, Wenning, Dion, Stephanie L., Kutny, Peter M., Zhang, Yingfan, Cheng, Albert W., Jillette, Nathaniel L., Malhotra, Ankit, Geurts, Aron M., Chen, Yi-Guang, Wang, Haoyi
格式: Artigo
語言:Inglês
出版: Genetics Society of America 2015
主題:
Communications
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4492369/
https://ncbi.nlm.nih.gov/pubmed/25819794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.115.176594
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