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Delivery of Cas9 protein into mouse zygotes through a series of electroporation dramatically increased the efficiency of model creation
Previously we established Zygote Electroporation of Nucleases (ZEN) technology as an efficient and high-throughput way to generate genetically modified mouse models. However, there were significant variations of the targeting efficiency among different genomic loci using our previously published pro...
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| Publicat a: | J Genet Genomics |
|---|---|
| Autors principals: | , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4892940/ https://ncbi.nlm.nih.gov/pubmed/27210041 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jgg.2016.02.004 |
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