Efficient CRISPR/Cas9-Mediated Genome Editing in Mice by Zygote Electroporation of Nuclease

The clustered regularly interspaced short palindromic repeat (CRISPR)/CRISPR-associated protein (Cas) system is an adaptive immune system in bacteria and archaea that has recently been exploited for genome engineering. Mutant mice can be generated in one step through direct delivery of the CRISPR/Ca...

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Sparad:
Bibliografiska uppgifter
I publikationen:Genetics
Huvudupphovsmän: Qin, Wenning, Dion, Stephanie L., Kutny, Peter M., Zhang, Yingfan, Cheng, Albert W., Jillette, Nathaniel L., Malhotra, Ankit, Geurts, Aron M., Chen, Yi-Guang, Wang, Haoyi
Materialtyp: Artigo
Språk:Inglês
Publicerad: Genetics Society of America 2015
Ämnen:
Communications
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4492369/
https://ncbi.nlm.nih.gov/pubmed/25819794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.115.176594
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