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Efficient CRISPR/Cas9-Mediated Genome Editing in Mice by Zygote Electroporation of Nuclease

The clustered regularly interspaced short palindromic repeat (CRISPR)/CRISPR-associated protein (Cas) system is an adaptive immune system in bacteria and archaea that has recently been exploited for genome engineering. Mutant mice can be generated in one step through direct delivery of the CRISPR/Ca...

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Bibliografische gegevens
Gepubliceerd in:Genetics
Hoofdauteurs: Qin, Wenning, Dion, Stephanie L., Kutny, Peter M., Zhang, Yingfan, Cheng, Albert W., Jillette, Nathaniel L., Malhotra, Ankit, Geurts, Aron M., Chen, Yi-Guang, Wang, Haoyi
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Genetics Society of America 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4492369/
https://ncbi.nlm.nih.gov/pubmed/25819794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.115.176594
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