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Relevance of ADAMTS13 to liver transplantation and surgery
A disintegrin-like and metalloproteinase with thrombospondin type-1 motifs 13 (ADAMTS13) specifically cleaves unusually-large von Willebrand factor (VWF) multimers under high shear stress, and down-regulates VWF function to form platelet thrombi. Deficiency of plasma ADAMTS13 activity induces a life...
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Publicado no: | World J Hepatol |
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Main Authors: | , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Baishideng Publishing Group Inc
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4491906/ https://ncbi.nlm.nih.gov/pubmed/26167250 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4254/wjh.v7.i13.1772 |
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