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Relevance of ADAMTS13 to liver transplantation and surgery

A disintegrin-like and metalloproteinase with thrombospondin type-1 motifs 13 (ADAMTS13) specifically cleaves unusually-large von Willebrand factor (VWF) multimers under high shear stress, and down-regulates VWF function to form platelet thrombi. Deficiency of plasma ADAMTS13 activity induces a life...

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Detalhes bibliográficos
Publicado no:World J Hepatol
Main Authors: Ko, Saiho, Chisuwa, Hisanao, Matsumoto, Masanori, Fujimura, Yoshihiro, Okano, Eiji, Nakajima, Yoshiyuki
Formato: Artigo
Idioma:Inglês
Publicado em: Baishideng Publishing Group Inc 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4491906/
https://ncbi.nlm.nih.gov/pubmed/26167250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4254/wjh.v7.i13.1772
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