von Willebrand Factor-Rich Platelet Thrombi in the Liver Cause Sinusoidal Obstruction Syndrome following Oxaliplatin-Based Chemotherapy

Oxaliplatin-based chemotherapy is widely used to treat advanced colorectal cancer (CRC). Sinusoidal obstruction syndrome (SOS) due to oxaliplatin is a serious type of chemotherapy-associated liver injury (CALI) in CRC patients. SOS is thought to be caused by the sinusoidal endothelial cell damage, w...

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Udgivet i:PLoS One
Main Authors: Nishigori, Naoto, Matsumoto, Masanori, Koyama, Fumikazu, Hayakawa, Masaki, Hatakeyayama, Kinta, Ko, Saiho, Fujimura, Yoshihiro, Nakajima, Yoshiyuki
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4651512/
https://ncbi.nlm.nih.gov/pubmed/26580395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0143136
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