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Determination of ADAMTS13 and Its Clinical Significance for ADAMTS13 Supplementation Therapy to Improve the Survival of Patients with Decompensated Liver Cirrhosis

The liver plays a central role in hemostasis by synthesizing clotting factors, coagulation inhibitors, and fibrinolytic proteins. Liver cirrhosis (LC), therefore, impacts on both primary and secondary hemostatic mechanisms. ADAMTS13 is a metalloproteinase, produced exclusively in hepatic stellate ce...

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Autori principali: Uemura, Masahito, Fujimura, Yoshihiro, Ko, Saiho, Matsumoto, Masanori, Nakajima, Yoshiyuki, Fukui, Hiroshi
Natura: Artigo
Lingua:Inglês
Pubblicazione: SAGE-Hindawi Access to Research 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3170842/
https://ncbi.nlm.nih.gov/pubmed/21994870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4061/2011/759047
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