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Analysis of the size dependence of macromolecular crowding shows that smaller is better
The aqueous milieu inside cells contains as much as 30–40% dissolved protein and RNA by volume. This large concentration of macromolecules is expected to cause significant deviations from solution ideality. In vivo biochemical reaction rates and equilibria might differ significantly from those measu...
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| 出版年: | Proc Natl Acad Sci U S A |
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| 第一著者: | |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4491746/ https://ncbi.nlm.nih.gov/pubmed/26080429 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1505396112 |
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