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Analysis of the size dependence of macromolecular crowding shows that smaller is better
The aqueous milieu inside cells contains as much as 30–40% dissolved protein and RNA by volume. This large concentration of macromolecules is expected to cause significant deviations from solution ideality. In vivo biochemical reaction rates and equilibria might differ significantly from those measu...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4491746/ https://ncbi.nlm.nih.gov/pubmed/26080429 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1505396112 |
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