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The effect of macromolecular crowding on chaperonin-mediated protein folding

The cylindrical chaperonin GroEL and its cofactor GroES mediate ATP-dependent protein folding in Escherichia coli. Recent studies in vitro demonstrated that GroES binding to GroEL causes the displacement of unfolded polypeptide into the central volume of the GroEL cavity for folding in a sequestrate...

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Bibliografiske detaljer
Main Authors: Martin, Jörg, Hartl, F.-Ulrich
Format: Artigo
Sprog:Inglês
Udgivet: The National Academy of Sciences of the USA 1997
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC19752/
https://ncbi.nlm.nih.gov/pubmed/9037014
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