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The effect of macromolecular crowding on chaperonin-mediated protein folding

The cylindrical chaperonin GroEL and its cofactor GroES mediate ATP-dependent protein folding in Escherichia coli. Recent studies in vitro demonstrated that GroES binding to GroEL causes the displacement of unfolded polypeptide into the central volume of the GroEL cavity for folding in a sequestrate...

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Detalhes bibliográficos
Main Authors: Martin, Jörg, Hartl, F.-Ulrich
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences of the USA 1997
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC19752/
https://ncbi.nlm.nih.gov/pubmed/9037014
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