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The effect of macromolecular crowding on chaperonin-mediated protein folding

The cylindrical chaperonin GroEL and its cofactor GroES mediate ATP-dependent protein folding in Escherichia coli. Recent studies in vitro demonstrated that GroES binding to GroEL causes the displacement of unfolded polypeptide into the central volume of the GroEL cavity for folding in a sequestrate...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Martin, Jörg, Hartl, F.-Ulrich
Format: Artigo
Sprache:Inglês
Veröffentlicht: The National Academy of Sciences of the USA 1997
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC19752/
https://ncbi.nlm.nih.gov/pubmed/9037014
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