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A Didactic Model of Macromolecular Crowding Effects on Protein Folding

A didactic model is presented to illustrate how the effect of macromolecular crowding on protein folding and association is modeled using current analytical theory and discrete molecular dynamics. While analytical treatments of crowding may consider the effect as a potential of average force acting...

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Detalhes bibliográficos
Main Authors: Tsao, Douglas, Minton, Allen P., Dokholyan, Nikolay V.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2914742/
https://ncbi.nlm.nih.gov/pubmed/20689808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0011936
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