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A Didactic Model of Macromolecular Crowding Effects on Protein Folding

A didactic model is presented to illustrate how the effect of macromolecular crowding on protein folding and association is modeled using current analytical theory and discrete molecular dynamics. While analytical treatments of crowding may consider the effect as a potential of average force acting...

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Bibliografiske detaljer
Main Authors: Tsao, Douglas, Minton, Allen P., Dokholyan, Nikolay V.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2914742/
https://ncbi.nlm.nih.gov/pubmed/20689808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0011936
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