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Crowding and hydrodynamic interactions likely dominate in vivo macromolecular motion
To begin to elucidate the principles of intermolecular dynamics in the crowded environment of cells, employing Brownian dynamics (BD) simulations, we examined possible mechanism(s) responsible for the great reduction in diffusion constants of macromolecules in vivo from that at infinite dilution. In...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2973006/ https://ncbi.nlm.nih.gov/pubmed/20937902 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1011354107 |
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