Mechanism of GTP hydrolysis by G-protein alpha subunits.

Hydrolysis of GTP by a variety of guanine nucleotide-binding proteins is a crucial step for regulation of these biological switches. Mutations that impair the GTPase activity of certain heterotrimeric signal-transducing G proteins or of p21ras cause tumors in man. A conserved glutamic residue in the...

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Detalles Bibliográficos

Publicado en:	Proc Natl Acad Sci U S A
Autores principales:	Kleuss, C, Raw, A S, Lee, E, Sprang, S R, Gilman, A G
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	National Academy of Sciences 1994
Materias:	Research Article
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC44910/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7937899/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.21.9828
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