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Regulation of cell cycle progression and nuclear affinity of the retinoblastoma protein by protein phosphatases.

Decreased affinity of the retinoblastoma protein (RB) for the nuclear compartment has been correlated with cell cycle-dependent phosphorylation of the RB protein during the G1/S phase of the cell cycle. We examined the effects of microinjected protein-serine/threonine phosphatases types 1 (PP1) and...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Alberts, A S, Thorburn, A M, Shenolikar, S, Mumby, M C, Feramisco, J R
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1993
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC45667/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8380637/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.2.388
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