Mechanism of GTP hydrolysis by G-protein alpha subunits.
Hydrolysis of GTP by a variety of guanine nucleotide-binding proteins is a crucial step for regulation of these biological switches. Mutations that impair the GTPase activity of certain heterotrimeric signal-transducing G proteins or of p21ras cause tumors in man. A conserved glutamic residue in the...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
1994
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC44910/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7937899/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.21.9828 |
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