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A Structural Overview of RNA-Dependent RNA Polymerases from the Flaviviridae Family

RNA-dependent RNA polymerases (RdRPs) from the Flaviviridae family are representatives of viral polymerases that carry out RNA synthesis through a de novo initiation mechanism. They share a ≈ 600-residue polymerase core that displays a canonical viral RdRP architecture resembling an encircled right...

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Bibliographic Details
Published in:Int J Mol Sci
Main Authors: Wu, Jiqin, Liu, Weichi, Gong, Peng
Format: Artigo
Language:Inglês
Published: MDPI 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4490480/
https://ncbi.nlm.nih.gov/pubmed/26062131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms160612943
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