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Structural basis of viral RNA-dependent RNA polymerase catalysis and translocation
Viral RNA-dependent RNA polymerases (RdRPs) play essential roles in viral genome replication and transcription. We previously reported several structural states of the poliovirus RdRP nucleotide addition cycle (NAC) that revealed a unique palm domain-based active site closure mechanism and proposed...
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| Published in: | Proc Natl Acad Sci U S A |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
2016
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4948327/ https://ncbi.nlm.nih.gov/pubmed/27339134 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1602591113 |
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