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A unique intra-molecular fidelity-modulating mechanism identified in a viral RNA-dependent RNA polymerase
Typically not assisted by proofreading, the RNA-dependent RNA polymerases (RdRPs) encoded by the RNA viruses may need to independently control its fidelity to fulfill virus viability and fitness. However, the precise mechanism by which the RdRP maintains its optimal fidelity level remains largely el...
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| 發表在: | Nucleic Acids Res |
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| Main Authors: | , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Oxford University Press
2018
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6237809/ https://ncbi.nlm.nih.gov/pubmed/30239956 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky848 |
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