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Nephron-specific deletion of the prorenin receptor causes a urine concentration defect

The prorenin receptor (PRR), a recently discovered component of the renin-angiotensin system, is expressed in the nephron in general and the collecting duct in particular. However, the physiological significance of nephron PRR remains unclear, partly due to developmental abnormalities associated wit...

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Veröffentlicht in:Am J Physiol Renal Physiol
Hauptverfasser: Ramkumar, Nirupama, Stuart, Deborah, Calquin, Matias, Quadri, Syed, Wang, Shuping, Van Hoek, Alfred N., Siragy, Helmy M., Ichihara, Atsuhiro, Kohan, Donald E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4490380/
https://ncbi.nlm.nih.gov/pubmed/25995108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00126.2015
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