Possible role for nephron‐derived angiotensinogen in angiotensin‐II dependent hypertension

The role of intranephron angiotensinogen (AGT) in blood pressure (BP) regulation is not fully understood. Previous studies showed that proximal tubule‐specific overexpression of AGT increases BP, whereas proximal tubule‐specific deletion of AGT did not alter BP. The latter study may not have complet...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Physiol Rep
Main Authors: Ramkumar, Nirupama, Stuart, Deborah, Calquin, Matias, Wang, Shuping, Niimura, Fumio, Matsusaka, Taiji, Kohan, Donald E.
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2016
Teme:
Original Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4760401/
https://ncbi.nlm.nih.gov/pubmed/26755736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.12675
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