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Liver Angiotensinogen Is the Primary Source of Renal Angiotensin II

Angiotensin II content in the kidney is much higher than in the plasma, and it increases more in kidney diseases through an uncertain mechanism. Because the kidney abundantly expresses angiotensinogen mRNA, transcriptional dysregulation of angiotensinogen within the kidney is one potential cause of...

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Bibliografske podrobnosti
Main Authors: Matsusaka, Taiji, Niimura, Fumio, Shimizu, Akihiro, Pastan, Ira, Saito, Akihiko, Kobori, Hiroyuki, Nishiyama, Akira, Ichikawa, Iekuni
Format: Artigo
Jezik:Inglês
Izdano: American Society of Nephrology 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3380650/
https://ncbi.nlm.nih.gov/pubmed/22518004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2011121159
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