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Liver Angiotensinogen Is the Primary Source of Renal Angiotensin II

Angiotensin II content in the kidney is much higher than in the plasma, and it increases more in kidney diseases through an uncertain mechanism. Because the kidney abundantly expresses angiotensinogen mRNA, transcriptional dysregulation of angiotensinogen within the kidney is one potential cause of...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Matsusaka, Taiji, Niimura, Fumio, Shimizu, Akihiro, Pastan, Ira, Saito, Akihiko, Kobori, Hiroyuki, Nishiyama, Akira, Ichikawa, Iekuni
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Nephrology 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3380650/
https://ncbi.nlm.nih.gov/pubmed/22518004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2011121159
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