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Liver Angiotensinogen Is the Primary Source of Renal Angiotensin II

Angiotensin II content in the kidney is much higher than in the plasma, and it increases more in kidney diseases through an uncertain mechanism. Because the kidney abundantly expresses angiotensinogen mRNA, transcriptional dysregulation of angiotensinogen within the kidney is one potential cause of...

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Detalhes bibliográficos
Main Authors: Matsusaka, Taiji, Niimura, Fumio, Shimizu, Akihiro, Pastan, Ira, Saito, Akihiko, Kobori, Hiroyuki, Nishiyama, Akira, Ichikawa, Iekuni
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3380650/
https://ncbi.nlm.nih.gov/pubmed/22518004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2011121159
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