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Liver Angiotensinogen Is the Primary Source of Renal Angiotensin II

Angiotensin II content in the kidney is much higher than in the plasma, and it increases more in kidney diseases through an uncertain mechanism. Because the kidney abundantly expresses angiotensinogen mRNA, transcriptional dysregulation of angiotensinogen within the kidney is one potential cause of...

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Главные авторы: Matsusaka, Taiji, Niimura, Fumio, Shimizu, Akihiro, Pastan, Ira, Saito, Akihiko, Kobori, Hiroyuki, Nishiyama, Akira, Ichikawa, Iekuni
Формат: Artigo
Язык:Inglês
Опубликовано: American Society of Nephrology 2012
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3380650/
https://ncbi.nlm.nih.gov/pubmed/22518004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2011121159
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