Oncolytic reovirus enhances rituximab-mediated antibody-dependent cellular cytotoxicity against chronic lymphocytic leukaemia

The naturally occurring oncolytic virus (OV), reovirus, replicates in cancer cells causing direct cytotoxicity, and can activate innate and adaptive immune responses to facilitate tumour clearance. Reovirus is safe, well tolerated and currently in clinical testing for the treatment of multiple myelo...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Leukemia
Päätekijät: Parrish, C, Scott, G B, Migneco, G, Scott, K J, Steele, L P, Ilett, E, West, E J, Hall, K, Selby, P J, Buchanan, D, Varghese, A, Cragg, M S, Coffey, M, Hillmen, P, Melcher, A A, Errington-Mais, F
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group 2015
Aiheet:
Original Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4490165/
https://ncbi.nlm.nih.gov/pubmed/25814029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2015.88
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