Oncolytic reovirus enhances rituximab-mediated antibody-dependent cellular cytotoxicity against chronic lymphocytic leukaemia

The naturally occurring oncolytic virus (OV), reovirus, replicates in cancer cells causing direct cytotoxicity, and can activate innate and adaptive immune responses to facilitate tumour clearance. Reovirus is safe, well tolerated and currently in clinical testing for the treatment of multiple myelo...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Leukemia
Main Authors: Parrish, C, Scott, G B, Migneco, G, Scott, K J, Steele, L P, Ilett, E, West, E J, Hall, K, Selby, P J, Buchanan, D, Varghese, A, Cragg, M S, Coffey, M, Hillmen, P, Melcher, A A, Errington-Mais, F
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2015
Teme:
Original Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4490165/
https://ncbi.nlm.nih.gov/pubmed/25814029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2015.88
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