Oncolytic reovirus enhances rituximab-mediated antibody-dependent cellular cytotoxicity against chronic lymphocytic leukaemia

The naturally occurring oncolytic virus (OV), reovirus, replicates in cancer cells causing direct cytotoxicity, and can activate innate and adaptive immune responses to facilitate tumour clearance. Reovirus is safe, well tolerated and currently in clinical testing for the treatment of multiple myelo...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Leukemia
Prif Awduron: Parrish, C, Scott, G B, Migneco, G, Scott, K J, Steele, L P, Ilett, E, West, E J, Hall, K, Selby, P J, Buchanan, D, Varghese, A, Cragg, M S, Coffey, M, Hillmen, P, Melcher, A A, Errington-Mais, F
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2015
Pynciau:
Original Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4490165/
https://ncbi.nlm.nih.gov/pubmed/25814029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2015.88
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