Oncolytic reovirus enhances rituximab-mediated antibody-dependent cellular cytotoxicity against chronic lymphocytic leukaemia

The naturally occurring oncolytic virus (OV), reovirus, replicates in cancer cells causing direct cytotoxicity, and can activate innate and adaptive immune responses to facilitate tumour clearance. Reovirus is safe, well tolerated and currently in clinical testing for the treatment of multiple myelo...

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Detalhes bibliográficos
Publicado no:Leukemia
Main Authors: Parrish, C, Scott, G B, Migneco, G, Scott, K J, Steele, L P, Ilett, E, West, E J, Hall, K, Selby, P J, Buchanan, D, Varghese, A, Cragg, M S, Coffey, M, Hillmen, P, Melcher, A A, Errington-Mais, F
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4490165/
https://ncbi.nlm.nih.gov/pubmed/25814029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2015.88
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