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Distinct sources of hematopoietic progenitors emerge before HSCs and provide functional blood cells in the mammalian embryo
Hematopoietic potential arises in mammalian embryos before adult-repopulating hematopoietic stem cells (HSCs). At E9.5, we show the first murine definitive erythro-myeloid progenitors (EMPs) have an immunophenotype distinct from primitive hematopoietic progenitors, maturing megakaryocytes and macrop...
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| 出版年: | Cell Rep |
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| 主要な著者: | , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2015
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4490098/ https://ncbi.nlm.nih.gov/pubmed/26095363 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.05.036 |
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