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Distinct sources of hematopoietic progenitors emerge before HSCs and provide functional blood cells in the mammalian embryo

Hematopoietic potential arises in mammalian embryos before adult-repopulating hematopoietic stem cells (HSCs). At E9.5, we show the first murine definitive erythro-myeloid progenitors (EMPs) have an immunophenotype distinct from primitive hematopoietic progenitors, maturing megakaryocytes and macrop...

詳細記述

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書誌詳細
出版年:Cell Rep
主要な著者: McGrath, Kathleen E., Frame, Jenna M., Fegan, Katherine H., Bowen, James R., Conway, Simon J., Catherman, Seana C., Kingsley, Paul D., Koniski, Anne D., Palis, James
フォーマット: Artigo
言語:Inglês
出版事項: 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4490098/
https://ncbi.nlm.nih.gov/pubmed/26095363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.05.036
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