P-selectin Inhibition Therapeutically Promotes Thrombus Resolution and Prevents Vein Wall Fibrosis Better than Enoxaparin and an Inhibitor to von Willebrand Factor

OBJECTIVE: Aptamers are oligonucleotides targeting protein/protein interactions with pharmacokinetic profiles and activity reversal options. Although P-selectin and von Willebrand factor (VWF) have been implicated in the development of venous thrombosis (VT), no studies have directly compared aptame...

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Xehetasun bibliografikoak
Argitaratua izan da:Arterioscler Thromb Vasc Biol
Egile Nagusiak: Diaz, Jose A., Wrobleski, Shirley K., Alvarado, Christine M., Hawley, Angela E., Doornbos, Nichole K., Lester, Patrick A., Lowe, Suzan E., Gabriel, Joy E., Roelofs, Karen J., Henke, Peter K., Schaub, Robert G., Wakefield, Thomas W., Myers, Daniel D.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2015
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4489932/
https://ncbi.nlm.nih.gov/pubmed/25657307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.114.304457
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