P-selectin Inhibition Therapeutically Promotes Thrombus Resolution and Prevents Vein Wall Fibrosis Better than Enoxaparin and an Inhibitor to von Willebrand Factor

OBJECTIVE: Aptamers are oligonucleotides targeting protein/protein interactions with pharmacokinetic profiles and activity reversal options. Although P-selectin and von Willebrand factor (VWF) have been implicated in the development of venous thrombosis (VT), no studies have directly compared aptame...

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Detalhes bibliográficos
Publicado no:Arterioscler Thromb Vasc Biol
Main Authors: Diaz, Jose A., Wrobleski, Shirley K., Alvarado, Christine M., Hawley, Angela E., Doornbos, Nichole K., Lester, Patrick A., Lowe, Suzan E., Gabriel, Joy E., Roelofs, Karen J., Henke, Peter K., Schaub, Robert G., Wakefield, Thomas W., Myers, Daniel D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4489932/
https://ncbi.nlm.nih.gov/pubmed/25657307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.114.304457
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