Microneedle patch delivery to the skin of virus-like particles containing heterologous M2e extracellular domains of influenza virus induces broad heterosubtypic cross-protection

A broadly cross-protective influenza vaccine that can be administrated by a painless self-immunization method would be a value as a potential universal mass vaccination strategy. This study developed a minimally-invasive microneedle (MN) patch for skin vaccination with virus-like particles containin...

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Vydáno v:J Control Release
Hlavní autoři: Kim, Min-Chul, Lee, Jeong Woo, Choi, Hyo-Jick, Lee, Yu-Na, Hwang, Hye Suk, Lee, Jongsang, Kim, Cheol, Lee, Jong Seok, Montemagno, Carlo, Prausnitz, Mark R., Kang, Sang-Moo
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4489561/
https://ncbi.nlm.nih.gov/pubmed/26003039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2015.05.278
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