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Cross Protection against Influenza A Virus by Yeast-Expressed Heterologous Tandem Repeat M2 Extracellular Proteins

The influenza M2 ectodomain (M2e) is well conserved across human influenza A subtypes, but there are few residue changes among avian and swine origin influenza A viruses. We expressed a tandem repeat construct of heterologous M2e sequences (M2e5x) derived from human, swine, and avian origin influenz...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Lee, Yu-Na, Kim, Min-Chul, Lee, Young-Tae, Hwang, Hye Suk, Lee, Jongsang, Kim, Cheol, Kang, Sang-Moo
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4569442/
https://ncbi.nlm.nih.gov/pubmed/26366729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0137822
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